In patients with locally advanced colorectal cancer, combining intensified chemotherapy with the dual-antibody drug cadonilimab increased the pathologic complete response rate (pCR) to 26.8%, nearly three times higher than the 9.8% rate with standard therapy. This phase 2 trial,
2026-05-19
A new photothermal nanoparticle developed by Chinese researchers reached 63.8°C after 5 minutes of irradiation with an 808-nm laser and was found to kill more than 92% of osteosarcoma cells. The IEICO-F nanoparticles, based on an acceptor-donor-acceptor (A-D-A) structure, increas
2026-05-19
Asta will invest a total of 8.3 billion won to strengthen its business capabilities and acquire a core database valued at 4 billion won. The agreement includes 14 mass spectrometers, patents for identifying antibiotic resistance, and 4,045 microbial strain specimens. The acquisit
2026-05-19
Japanese researchers identified the ZFP384 gene, which stops brain recovery several months after stroke onset, and developed an antisense oligonucleotide (ASO) therapy to inhibit it. The therapy prevented loss of function in brain-repair cells and successfully improved motor func
2026-05-19
Analysis of more than 45,000 tumor samples classified cancer into three types based on TP53 mutations. The analysis identified 95 key mutated genes and led to the proposal of two precision medicine strategies. It also completed a map of 47 signaling pathways across 52 cancer type
2026-05-19
A new mechanism by which statins, drugs used to treat hyperlipidemia, may treat autoimmune diseases has been published in the international journal Immunity (IF 26.3). Pitavastatin suppresses a specific pathway in T cells, thereby preventing the generation of hyperactivated folli
2026-05-19
Researchers at Indiana University School of Medicine found that hematopoietic stem cells are sensitive to oxygen levels and have the strongest engraftment capacity when cultured in a 1% hypoxic environment similar to conditions in the body. Cells exposed to the 21% oxygen concent
2026-05-19
A 21-amino acid peptide from the capsid protein of porcine circovirus type 2 (PCV2) has opened up the possibility of a universal vaccine platform. The nanoparticle works by activating cellular autophagy and tumor necrosis factor (TNF-α) signaling, thereby enhancing antigen presen
2026-05-19
GC Biopharma became the first company in South Korea to replace a WHO GMP on-site inspection with a document review and obtain final approval, reducing costs by more than 50%. The approval covers the influenza vaccine GC Flu and the varicella vaccine Varicella in a routine inspec
2026-05-19
Serum amyloid A1 (SAA1) protein has been identified as a cause of immunotherapy resistance in renal cell carcinoma. SAA1 induces immune evasion by forming NETs, a “trap” that blocks T-cell attacks, and is activated through the TLR2 signaling pathway. Inhibiting SAA1 restored the
2026-05-19
